It's the first full-fixture weekend of the season, as the Evo-Stik Northern Premier League kicks off this Saturday.
In the Premier Division, Matlock are the only Derbyshire side commencing their season at home, as the Gladiators welcome Lancaster City to the Autoworld Arena.
Buxton and Mickleover, meanwhile, begin their campaigns on the road, travelling to Whitby Town and Stalybridge Celtic for their respective opening fixtures.
Although the Evo-Stik League has experience restructuring, the line-up for Derbyshire continues to be the same.
In the East Division lie Belper Town and Gresley, who will host Morpeth Town and visit Brighouse Town respectively.
Glossop North End complete Derbyshire's Northern Premier League line-up, with the Hillmen hosting Atherton Collieries in their West Division opener.
In the Sky Bet Championship, Derby return to league action after a 2-0 win at Oldham in the Carabao Cup on Tuesday night; the Rams visit winless Millwall hoping to correct their heavy 4-1 defeat to Leeds last weekend.
Chesterfield will also be looking to make up for mistakes, with 1300 Spireites making the trip to see Martin Allen's side face newly-promoted Salford City in the National League on the back of a 3-2 midweek loss at Barrow.
After being unable to make it consecutive victories in the National League North on Tuesday, Billy Heath's Alfreton have a tough home fixture in the visit of Blyth Spartans, who are level on points with the Reds as it stands.
In the Midland Football League Premier Division, joint-table toppers Ilkeston Town are hopeful of notching a fourth win from their opening five league fixtures when they visit Walsall Wood on the back of a 2-0 derby win over Long Eaton United.
The Blues, meanwhile, return home to host Highgate United, whilst bottom-of-the-league South Normanton look for their first points of the season in their visit to Stourport Swifts.
Also yet to find their first league victory are NCEL Premier Division side Staveley, who make the trip to Harrogate Railway Athletic on the back of a 2-0 midweek defeat at Yorkshire Amateur.